|
| Titre : |
Basic clinical radiobiology |
| Type de document : |
texte imprimé |
| Auteurs : |
Michael Joiner ; Albert van der Kogel |
| Mention d'édition : |
Fifth edition. |
| Editeur : |
Boca Raton : CRC Press |
| Année de publication : |
2018 |
| Importance : |
1 vol. (350 p.) |
| Format : |
29 cm |
| ISBN/ISSN/EAN : |
978-0-429-95540-2 |
| Langues : |
Anglais (eng) |
| Catégories : |
Physique
|
| Mots-clés : |
Physique |
| Index. décimale : |
615.8 Thérapies et catégories de thérapies particulières |
| Résumé : |
Basic Clinical Radiobiology is a concise but comprehensive textbook setting out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics, and radiation technology.
Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, this fifth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer.
This new edition is highly illustrated with attractive 2-colour presentation and now includes new chapters on stem cells, tissue response and the convergence of radiotherapy, radiobiology, and physics. It will be invaluable for FRCR (clinical oncology) and equivalent candidates, SpRs (and equivalent) in radiation oncology, practicing radiation oncologists and radiotherapists, as well as radiobiologists and radiotherapy physicists. |
| Note de contenu : |
Preface
Contributors
1. Introduction: The significance of radiobiology and radiotherapy for cancer treatment
Michael C. Joiner, Albert J. van der Kogel and G. Gordon Steel
2. Irradiation-induced damage and the DNA damage response
Conchita Vens, Marianne Koritzinsky and Bradly G. Wouters
3. Cell death after irradiation: How, when and why cells die
Bradly G. Wouters
4. Quantifying cell kill and cell survival
Michael C. Joiner
5. Radiation dose-response relationships
Søren M. Bentzen
6. Linear energy transfer and relative biological effectiveness
Michael C. Joiner, Jay W. Burmeister and Wolfgang Dörr
7. Physics of radiation therapy for the radiobiologist
Jay W. Burmeister and Michael C. Joiner
8. Tumour growth and response to radiation
Daniel Zips
9. Fractionation: The linear-quadratic approach
Michael C. Joiner and Søren M. Bentzen
10. The linear-quadratic approach in clinical practice
Søren M. Bentzen and Michael C. Joiner
11. Modified fractionation
Michael Baumann, Mechthild Krause and Vincent Grégoire
12. Time factors in normal tissue responses to irradiation
Wolfgang Dörr
13. The dose-rate effect
Albert J. van der Kogel and Michael C. Joiner
14. Pathogenesis of normal tissue side effects
Wolfgang Dörr
15. Stem cells in radiotherap
Robert P. Coppes, Michael Baumann, Mechthild Krause and Richard P. Hill
6. Normal tissue tolerance and the effect of dose inhomogeneities
Wolfgang Dörr and Albert J. van der Kogel
17. The oxygen effect and therapeutic approaches to tumour hypoxia
Michael R. Horsman, J. Martin Brown, Albert J. van der Kogel, Bradly G. Wouters and Jens Overgaard
18. The tumour microenvironment and cellular hypoxia responses
Bradly G. Wouters, Marianne Koritzinsky, J. Martin Brown and Albert J. van der Kogel
19. Combined radiotherapy and chemotherapy
Vincent Grégoire, Jean-Pascal Machiels and Michael Baumann
20. Molecular targeted agents for enhancing tumour response
Michael Baumann, Mechthild Krause and Vincent Grégoire
21. Biological individualisation of radiotherapy
Catharine M.L. West, Robert G. Bristow and Adrian C. Begg
22. Molecular image guided radiotherapy
Vincent Grégoire, Karin Haustermans and John Lee
23. Retreatment tolerance of normal tissues
Wolfgang Dörr, Dorota Gabryś and Fiona A. Stewart
24. Biological response modification of normal tissue reactions: Basic principles and pitfalls
Wolfgang Dörr
25. Hadron therapy: The clinical aspects
Vincent Grégoire, Jay W. Burmeister, Michael C. Joiner and Wolfgang Dörr
26. Tissue response models
Peter van Luijk, Wolfgang Dörr and Albert J. van der Kogel
27. Second cancers after radiotherapy
Klaus Rüdiger Trott and Wolfgang Dörr
Glossary
|
| Côte titre : |
Fs/24464 |
Basic clinical radiobiology [texte imprimé] / Michael Joiner ; Albert van der Kogel . - Fifth edition. . - Boca Raton : CRC Press, 2018 . - 1 vol. (350 p.) ; 29 cm. ISBN : 978-0-429-95540-2 Langues : Anglais ( eng)
| Catégories : |
Physique
|
| Mots-clés : |
Physique |
| Index. décimale : |
615.8 Thérapies et catégories de thérapies particulières |
| Résumé : |
Basic Clinical Radiobiology is a concise but comprehensive textbook setting out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics, and radiation technology.
Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, this fifth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer.
This new edition is highly illustrated with attractive 2-colour presentation and now includes new chapters on stem cells, tissue response and the convergence of radiotherapy, radiobiology, and physics. It will be invaluable for FRCR (clinical oncology) and equivalent candidates, SpRs (and equivalent) in radiation oncology, practicing radiation oncologists and radiotherapists, as well as radiobiologists and radiotherapy physicists. |
| Note de contenu : |
Preface
Contributors
1. Introduction: The significance of radiobiology and radiotherapy for cancer treatment
Michael C. Joiner, Albert J. van der Kogel and G. Gordon Steel
2. Irradiation-induced damage and the DNA damage response
Conchita Vens, Marianne Koritzinsky and Bradly G. Wouters
3. Cell death after irradiation: How, when and why cells die
Bradly G. Wouters
4. Quantifying cell kill and cell survival
Michael C. Joiner
5. Radiation dose-response relationships
Søren M. Bentzen
6. Linear energy transfer and relative biological effectiveness
Michael C. Joiner, Jay W. Burmeister and Wolfgang Dörr
7. Physics of radiation therapy for the radiobiologist
Jay W. Burmeister and Michael C. Joiner
8. Tumour growth and response to radiation
Daniel Zips
9. Fractionation: The linear-quadratic approach
Michael C. Joiner and Søren M. Bentzen
10. The linear-quadratic approach in clinical practice
Søren M. Bentzen and Michael C. Joiner
11. Modified fractionation
Michael Baumann, Mechthild Krause and Vincent Grégoire
12. Time factors in normal tissue responses to irradiation
Wolfgang Dörr
13. The dose-rate effect
Albert J. van der Kogel and Michael C. Joiner
14. Pathogenesis of normal tissue side effects
Wolfgang Dörr
15. Stem cells in radiotherap
Robert P. Coppes, Michael Baumann, Mechthild Krause and Richard P. Hill
6. Normal tissue tolerance and the effect of dose inhomogeneities
Wolfgang Dörr and Albert J. van der Kogel
17. The oxygen effect and therapeutic approaches to tumour hypoxia
Michael R. Horsman, J. Martin Brown, Albert J. van der Kogel, Bradly G. Wouters and Jens Overgaard
18. The tumour microenvironment and cellular hypoxia responses
Bradly G. Wouters, Marianne Koritzinsky, J. Martin Brown and Albert J. van der Kogel
19. Combined radiotherapy and chemotherapy
Vincent Grégoire, Jean-Pascal Machiels and Michael Baumann
20. Molecular targeted agents for enhancing tumour response
Michael Baumann, Mechthild Krause and Vincent Grégoire
21. Biological individualisation of radiotherapy
Catharine M.L. West, Robert G. Bristow and Adrian C. Begg
22. Molecular image guided radiotherapy
Vincent Grégoire, Karin Haustermans and John Lee
23. Retreatment tolerance of normal tissues
Wolfgang Dörr, Dorota Gabryś and Fiona A. Stewart
24. Biological response modification of normal tissue reactions: Basic principles and pitfalls
Wolfgang Dörr
25. Hadron therapy: The clinical aspects
Vincent Grégoire, Jay W. Burmeister, Michael C. Joiner and Wolfgang Dörr
26. Tissue response models
Peter van Luijk, Wolfgang Dörr and Albert J. van der Kogel
27. Second cancers after radiotherapy
Klaus Rüdiger Trott and Wolfgang Dörr
Glossary
|
| Côte titre : |
Fs/24464 |
|  |
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