Titre :	A Novel mechanical approach to wound closure: design and Evaluation of A bilateral external tension device
Type de document :	document électronique
Auteurs :	Nour El Houda Semcheddine, Auteur ; Karbab,Ahlem, Directeur de thèse
Editeur :	Sétif [Algérie] : Faculté des sciences de la Nature et de la vie, Université Ferhat Abbas Sétif 1
Année de publication :	2025
Importance :	37 Feuilles
Format :	PDF
ISBN/ISSN/EAN :	MS/2514
Langues :	Anglais
Catégories :	Thèse et mémoire:Master:Immunologie
Mots-clés :	Wounds  Scars  Wound healing  Surgical sutures  Tension.
Résumé :	Wounds are injuries or breaks in the integrity of the skin or deep tissues, resulting from various factors such as accidents, surgical interventions, or certain chronic diseases. They vary in type, depth, and severity. Wounds are considered health problems that often require precise medical intervention due to potential complications such as infection, delayed wound healing, and the formation of pathological scars. Therefore, the method of wound closure becomes a fundamental element in the success of treatment and in improving functional and cosmetic postoperative outcomes. This wound closure mechanism is based on a theoretical study of healing mechanisms, focusing on the interaction between cellular and mechanical factors, particularly the role of tension forces in bringing wound edges closer together and regenerating tissues. On the practical side, a unique device has been designed and developed for sutureless, non-surgical wound closure. It is characterized by the gradual and controlled application of tension, which maintains the stability of the wound edges and minimizes skin stretching. Experimental results have demonstrated the device's effectiveness in accelerating the healing process, reducing inflammation, and preventing scarring, compared to traditional closure methods. The study concludes that traction closure is a promising and safe technique for wound treatment, with potential for development and application in clinical practice. To analyze the need for this device and assess its adoptability, a survey was conducted targeting all segments of the population (1407 respondents). The results of this online survey were as follows: 61.3% expressed pain and fear associated with traditional suturing; 60.7% indicated that pain reduction was the most important factor in wound treatment; and 54.7% noted that scarring after surgery was bothersome, demonstrating their concern for the cosmetic aspect. In contrast, 85.9% expressed their willingness to try more comfortable and easier alternative solutions. This device represents a small but significant advancement in the treatment of superficial and intermediate wounds, relying on the integration of theoretical knowledge of wound healing physiology with principles of mechanical design and biomedical engineering. The goal is to produce a simple and effective device that can be easily used, even by non-specialists, in emergency situations. This study aims to integrate theoretical knowledge of wounds, healing mechanisms, and influencing factors with the practical application of developing a prototype of this new device. The study also seeks to evaluate the device's effectiveness compared to traditional methods and highlight the future potential for developing innovative medical equipment based on simple and effective principles to meet the needs of the healthcare sector and serve humanity.

A Novel mechanical approach to wound closure: design and Evaluation of A bilateral external tension device [document électronique] / Nour El Houda Semcheddine, Auteur ; Karbab,Ahlem, Directeur de thèse . - Sétif (Algérie) : Faculté des sciences de la Nature et de la vie, Université Ferhat Abbas Sétif 1, 2025 . - 37 Feuilles ; PDF.
ISSN : MS/2514
Langues : Anglais

Catégories :	Thèse et mémoire:Master:Immunologie
Mots-clés :	Wounds  Scars  Wound healing  Surgical sutures  Tension.
Résumé :	Wounds are injuries or breaks in the integrity of the skin or deep tissues, resulting from various factors such as accidents, surgical interventions, or certain chronic diseases. They vary in type, depth, and severity. Wounds are considered health problems that often require precise medical intervention due to potential complications such as infection, delayed wound healing, and the formation of pathological scars. Therefore, the method of wound closure becomes a fundamental element in the success of treatment and in improving functional and cosmetic postoperative outcomes. This wound closure mechanism is based on a theoretical study of healing mechanisms, focusing on the interaction between cellular and mechanical factors, particularly the role of tension forces in bringing wound edges closer together and regenerating tissues. On the practical side, a unique device has been designed and developed for sutureless, non-surgical wound closure. It is characterized by the gradual and controlled application of tension, which maintains the stability of the wound edges and minimizes skin stretching. Experimental results have demonstrated the device's effectiveness in accelerating the healing process, reducing inflammation, and preventing scarring, compared to traditional closure methods. The study concludes that traction closure is a promising and safe technique for wound treatment, with potential for development and application in clinical practice. To analyze the need for this device and assess its adoptability, a survey was conducted targeting all segments of the population (1407 respondents). The results of this online survey were as follows: 61.3% expressed pain and fear associated with traditional suturing; 60.7% indicated that pain reduction was the most important factor in wound treatment; and 54.7% noted that scarring after surgery was bothersome, demonstrating their concern for the cosmetic aspect. In contrast, 85.9% expressed their willingness to try more comfortable and easier alternative solutions. This device represents a small but significant advancement in the treatment of superficial and intermediate wounds, relying on the integration of theoretical knowledge of wound healing physiology with principles of mechanical design and biomedical engineering. The goal is to produce a simple and effective device that can be easily used, even by non-specialists, in emergency situations. This study aims to integrate theoretical knowledge of wounds, healing mechanisms, and influencing factors with the practical application of developing a prototype of this new device. The study also seeks to evaluate the device's effectiveness compared to traditional methods and highlight the future potential for developing innovative medical equipment based on simple and effective principles to meet the needs of the healthcare sector and serve humanity.