Anticoagulant and antithrombotic activities of Anabasis articulata decoction / Maria Ikhlef / Sétif : Faculté des Sciences de la Nature et de la Vie (2024)

Public ISBD Titre : Anticoagulant and antithrombotic activities of Anabasis articulata decoction Type de document : document électronique Auteurs : Maria Ikhlef, Auteur ; Khaoula Harmili, Auteur ; Amel Bouaziz., Directeur de thèse Editeur : Sétif : Faculté des Sciences de la Nature et de la Vie Année de publication : 2024 Importance : 37 Feuilles ISBN/ISSN/EAN : MS/2040 Langues : Anglais Catégories : Thèse et mémoire:Master:Physiologie cellulaire et physiopathologie Mots-clés : Anabasis articulata  Aqueous extract  Anticoagulant activity  Thrombosis  Prothrombin time. Résumé : This study aims to evaluate the anticoagulant and the antithrombotic activities of the aqueous extract of Anabasis articulata obtained from M’sila, Algeria. It is a desert plant belonging to the Chenopodiaceae family which is widely used in folk medicine for its valuable medicinal properties. The anticoagulant and antithrombotic activities of Anabasis articulata aqueous extract were evaluated compared with the negative control H2O and the positive control citrate on clotting time, thrombolytic activity, prothrombin time in different concentrations. The results of clotting time showed that Anabasis articulata significantly prolonged the clotting time at concentrations of 10, 20, and 50 mg/ml to 10.33±0.57 and 10.16±0.28 and 5.66±2.8 min, respctively. For the thrombolytic activity test , the results showed that the concentration of 50 mg/ml showed a stronger thrombolytic activity compared to the concentrations of 20 and 10 mg/ml with values of 35.58±0.69 and 8.93 ± 0.91 and 7.81 ± 1.81%, respectively. In thromboplasin time test, Anabasis articulata aqueous extract showed that the concentration of 50 mg/ml has good thromboplasin time of 5.73±0.92min. From these results, we conclude that Anabasis articulata extract possesses anticoagulant and antithrombotic activities because it contains biologically active compounds that can be exploited in the treatment of blood clotting disorders. Anticoagulant and antithrombotic activities of Anabasis articulata decoction [document électronique] / Maria Ikhlef, Auteur ; Khaoula Harmili, Auteur ; Amel Bouaziz., Directeur de thèse . - Sétif : Faculté des Sciences de la Nature et de la Vie, 2024 . - 37 Feuilles. ISSN : MS/2040 Langues : Anglais Catégories : Thèse et mémoire:Master:Physiologie cellulaire et physiopathologie Mots-clés : Anabasis articulata  Aqueous extract  Anticoagulant activity  Thrombosis  Prothrombin time. Résumé : This study aims to evaluate the anticoagulant and the antithrombotic activities of the aqueous extract of Anabasis articulata obtained from M’sila, Algeria. It is a desert plant belonging to the Chenopodiaceae family which is widely used in folk medicine for its valuable medicinal properties. The anticoagulant and antithrombotic activities of Anabasis articulata aqueous extract were evaluated compared with the negative control H2O and the positive control citrate on clotting time, thrombolytic activity, prothrombin time in different concentrations. The results of clotting time showed that Anabasis articulata significantly prolonged the clotting time at concentrations of 10, 20, and 50 mg/ml to 10.33±0.57 and 10.16±0.28 and 5.66±2.8 min, respctively. For the thrombolytic activity test , the results showed that the concentration of 50 mg/ml showed a stronger thrombolytic activity compared to the concentrations of 20 and 10 mg/ml with values of 35.58±0.69 and 8.93 ± 0.91 and 7.81 ± 1.81%, respectively. In thromboplasin time test, Anabasis articulata aqueous extract showed that the concentration of 50 mg/ml has good thromboplasin time of 5.73±0.92min. From these results, we conclude that Anabasis articulata extract possesses anticoagulant and antithrombotic activities because it contains biologically active compounds that can be exploited in the treatment of blood clotting disorders.

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Anticoagulant and antithrombotic activities of Anabasis articulata ethanolic extract / Rahil Bezzih / Sétif : Faculté des Sciences de la Nature et de la Vie (2024)

Public ISBD Titre : Anticoagulant and antithrombotic activities of Anabasis articulata ethanolic extract Type de document : document électronique Auteurs : Rahil Bezzih, Auteur ; Houda Boudjelida, Auteur ; Amel Bouaziz., Directeur de thèse Editeur : Sétif : Faculté des Sciences de la Nature et de la Vie Année de publication : 2024 Importance : 40 Feuilles ISBN/ISSN/EAN : MS/2037 Langues : Anglais Catégories : Thèse et mémoire:Master:Physiologie cellulaire et physiopathologie Mots-clés : Anabasis articulata  Anticoagulant activity  Antithrombotic activity  Clotting time. Résumé : This study was conducted to evaluate the anticoagulant and antithrombotic activities of Anabasis articulata (Chenopodiaceae), which is abundant in the desert and known as “Ajram”. The tests were conducted using ethanolic extract of A.articulata at different concentrations and applied to the plasma of healthy individuals. The prothrombin time, clotting time, and thrombolytic activity were measured. The results indicate that the ethanolic extract of the plant A. articulata can extend clotting time to 0.05 ± 5.42 minutes at a concentration of 50 mg/mL, which is an optimal concentration compared to the positive control (sodium citrate) that did not show any clotting. Additionally, the same extract demonstrated a concentration-dependent effect on plasma clotting time, with a negative correlation between the two. Furthermore, the ethanolic extract of A. articulata delays blood clotting by 10.66 ± 3.07 minutes at a concentration of 20 mg/mL, which is more effective than the positive control (sodium citrate) that showed no clotting. Moreover, the extract exhibited strong anticoagulant activity with a value of 8.63 ± 0.46% at a concentration of 50 mg/mL, compared to sodium citrate 0.69 ± 35.58%. In conclusion, these results can be considered very promising and call for further research and studies in order to produce a more effective and less side effect plant based anticoagulant. Anticoagulant and antithrombotic activities of Anabasis articulata ethanolic extract [document électronique] / Rahil Bezzih, Auteur ; Houda Boudjelida, Auteur ; Amel Bouaziz., Directeur de thèse . - Sétif : Faculté des Sciences de la Nature et de la Vie, 2024 . - 40 Feuilles. ISSN : MS/2037 Langues : Anglais Catégories : Thèse et mémoire:Master:Physiologie cellulaire et physiopathologie Mots-clés : Anabasis articulata  Anticoagulant activity  Antithrombotic activity  Clotting time. Résumé : This study was conducted to evaluate the anticoagulant and antithrombotic activities of Anabasis articulata (Chenopodiaceae), which is abundant in the desert and known as “Ajram”. The tests were conducted using ethanolic extract of A.articulata at different concentrations and applied to the plasma of healthy individuals. The prothrombin time, clotting time, and thrombolytic activity were measured. The results indicate that the ethanolic extract of the plant A. articulata can extend clotting time to 0.05 ± 5.42 minutes at a concentration of 50 mg/mL, which is an optimal concentration compared to the positive control (sodium citrate) that did not show any clotting. Additionally, the same extract demonstrated a concentration-dependent effect on plasma clotting time, with a negative correlation between the two. Furthermore, the ethanolic extract of A. articulata delays blood clotting by 10.66 ± 3.07 minutes at a concentration of 20 mg/mL, which is more effective than the positive control (sodium citrate) that showed no clotting. Moreover, the extract exhibited strong anticoagulant activity with a value of 8.63 ± 0.46% at a concentration of 50 mg/mL, compared to sodium citrate 0.69 ± 35.58%. In conclusion, these results can be considered very promising and call for further research and studies in order to produce a more effective and less side effect plant based anticoagulant.

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Anticoagulant and antithrombotic activities of Centaurea diluta decoction / Sana Hadi / Sétif [Algérie] : Faculté des sciences de la Nature et de la vie, Université Ferhat Abbas Sétif 1 (2024) 

Public ISBD Titre : Anticoagulant and antithrombotic activities of Centaurea diluta decoction Type de document : document électronique Auteurs : Sana Hadi, Auteur ; Maroua Boudjeris, Auteur ; Khalissa Medjref, Auteur ; Amel Bouaziz., Directeur de thèse Editeur : Sétif [Algérie] : Faculté des sciences de la Nature et de la vie, Université Ferhat Abbas Sétif 1 Année de publication : 2024 Importance : 31 Feuilles Format : PDF ISBN/ISSN/EAN : MS/2018 Langues : Anglais Catégories : Thèse et mémoire:Master:Physiologie cellulaire et physiopathologie Mots-clés : - Centaurea diluta - Anticoagulant activity - Clotting time - Prothrombin time Thrombolysis Résumé : The Aim of this study is to estimate the anticoagulant and the antithrombotic activities of the aqueous extract of C. diluta, an endemic plant belonging to Asteraceae family. The plasma of healthy volunteers was used in order to apply three tests, which are the time, prothrombin time, coagulation time and thrombolysis activity. The results showed that C. diluta decoction has the ability to prolong the clotting time at the concentration 50 mg/ml to24,33±1,88 min. As for prothrombin time, 10 and 20 mg/ml concentrations do not significantly affect coagulation, while 50 mg/ml concentration has a strong effect with value of 12,76±1,91 sec, which indicated that high concentrations are able of exerting anticoagulant activity. In the thrombolysis test, the extract showed a moderate ability to lyses the thrombosis with best effect at a concentration 50 mg/ml 20,86±0,31%. The results obtained support the idea of using this plant in folk medicine as anticoagulant agent. En ligne : http://dspace.univ-setif.dz:8888/jspui/bitstream/123456789/5735/1/PCP-CD182----M [...] Anticoagulant and antithrombotic activities of Centaurea diluta decoction [document électronique] / Sana Hadi, Auteur ; Maroua Boudjeris, Auteur ; Khalissa Medjref, Auteur ; Amel Bouaziz., Directeur de thèse . - Sétif (Algérie) : Faculté des sciences de la Nature et de la vie, Université Ferhat Abbas Sétif 1, 2024 . - 31 Feuilles ; PDF. ISSN : MS/2018 Langues : Anglais Catégories : Thèse et mémoire:Master:Physiologie cellulaire et physiopathologie Mots-clés : - Centaurea diluta - Anticoagulant activity - Clotting time - Prothrombin time Thrombolysis Résumé : The Aim of this study is to estimate the anticoagulant and the antithrombotic activities of the aqueous extract of C. diluta, an endemic plant belonging to Asteraceae family. The plasma of healthy volunteers was used in order to apply three tests, which are the time, prothrombin time, coagulation time and thrombolysis activity. The results showed that C. diluta decoction has the ability to prolong the clotting time at the concentration 50 mg/ml to24,33±1,88 min. As for prothrombin time, 10 and 20 mg/ml concentrations do not significantly affect coagulation, while 50 mg/ml concentration has a strong effect with value of 12,76±1,91 sec, which indicated that high concentrations are able of exerting anticoagulant activity. In the thrombolysis test, the extract showed a moderate ability to lyses the thrombosis with best effect at a concentration 50 mg/ml 20,86±0,31%. The results obtained support the idea of using this plant in folk medicine as anticoagulant agent. En ligne : http://dspace.univ-setif.dz:8888/jspui/bitstream/123456789/5735/1/PCP-CD182----M [...]

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Antioxidant, anti-inflammatory and antiulcerogenic activities of Anabasis articulata (Forssk.) Moq.extracts / Yasmina Makhlouf / Sétif : Faculté des Sciences de la Nature et de la Vie (2024) 

Public ISBD Titre : Antioxidant, anti-inflammatory and antiulcerogenic activities of Anabasis articulata (Forssk.) Moq.extracts Type de document : document électronique Auteurs : Yasmina Makhlouf, Auteur ; Amel Bouaziz., Directeur de thèse Editeur : Sétif : Faculté des Sciences de la Nature et de la Vie Année de publication : 2024 Importance : 1vol.(166f.) / ill.en coul Format : DVD. ISBN/ISSN/EAN : DOC-E/291 Langues : Français Catégories : Thèse et mémoire:Doctorat:Département de biologie et physiologie animale Mots-clés : Anabasis articulata  Analgesic  Gastric ulcer. Résumé : the aim of the present study was to investigate the antioxidant, anti-inflammatory, analgesic and anti-ulcerogenic activities of several extracts of Anabasis articulata, a plant from the Algerian flora of arid and semi-arid regions belonging to the Chenopodiaceae family selected on the basis of an ethnobotanical survey (n=182 respondents) conducted at the El-Mergueb nature reserve.Identification of biomolecules, quantification of secondary metabolites and performance of eight tests to study the antioxidant activity of the extracts: Total antioxidant capacity (TAC),DPPH- 2,2-diphenyl- 1picrylhydrazyl ; ABTS - 2,2′-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid, hydroxyl radical scavenging, metal-chelating hydrogen peroxide scavenging, reducing power test and β-carotene bleaching assay.In vitro anti-inflammatory activity was attested using the ovalbumin denaturation and BSA assay for DEAA,EEAA and their fractions .Molecular docking was performed using Autodock vina. Single oral doses of 2000 and 5000 mg/kg body weight were administered to albino mice to assess acute toxicity. The anti-inflammatory effect was assessed using the carrageenan-induced paw edema model in rats, the croton oil-induced ear edema model and the xylene-induced ear edema model in mice. Analgesic activity was achieved by intraperitoneal injection of acetic acid. Gastroprotective activity was assessed using ethanol-induced gastric ulceration in rats at doses of 50, 100 and 200 mg/kg p.o. for DEAA and 200,400 and 600 mg/kg p.o.for EEAA. The mechanistic study involved pretreatment with appropriate antagonists/ inhibitors such as glibenclamide , indomethacin and L-NAME. 46 plant species belonging to 23 botanical families were identified for the treatment of various ailments.Seven metabolites present in the n-butanol,ethyl acetate and chloroform fractions were qualitatively identified by LC-MS-MS:anthrone,beta-carotene, butylhydroxyanisole, butylhydroxytoluene,gallic acid,myricetin and rutin.The results showed that ChFA represents the largest quantity of total polyphenols and flavonoids. The n-butanol fraction showed the highest amount of total tannins. Quantitative evaluation of DPPH scavenging capacity showed that the ethanolic extract was the most active with IC50 values of 0.074±0.003 mg/mL, the chloroform fraction (ChFA) had the strongest effect in TAC, hydroxyl radical scavenging and hydrogen peroxide scavenging activity with EC50= 0.151±0.0017, IC50= 0.361±0.0087 and IC50= 1.777±0.0402 mg/mL), however,the nbutanol fraction had the highest activity in the ABTS radical scavenging test with an IC50 of 0.021±0.0007 mg/mL. All extracts showed good inhibition of linoleic acid oxidation. Good in vitro anti-inflammatory activity was attested using the ovalbumin denaturation and BSA assays for DEAA,EEAA and their fractions. Molecular docking of the identified biomolecules and the reference drug (indomethacin) revealed good interaction with the inflammatory protein COX2(3LN0).Acute toxicity testing showed that DEAA and EEAA did not cause mortality or adverse effects. Oral administration of 100 or 200 mg/kg of DEAA and EEAA to rats and mice inhibited edema in three tests,with good percentages for both doses of both extracts.The analgesic activity result showed a good effect compared with the standard analgesic (aspirin) for the same doses and extracts. Oral administration of DEAA at doses of 100 mg/kg or 200 mg/kg protected the gastric mucosa against absolute ethanol. Pretreatment with L-NAME,an inhibitor of nitric oxide synthesis, indomethacin,an inhibitor of prostaglandin production,or glibenclamide ,a KATP channel blocker,reversed the gastroprotective activity of (DEAA200 mg/kg, p.o.).DEAA effectively reduced basal gastric juice production without any effect on total acidity. The gastroprotective action of DEAA involved an increase in antioxidant enzymes and mucus secretion. This study provides for the first time the scientific basis for the traditional use of this plant for gastro-preventive effect and supports the traditional use of this plant to treat certain disorders linked to inflammation and oxidative stress.These results can be exploited in the pharmaceutical,food En ligne : http://dspace.univ-setif.dz:8888/jspui/bitstream/123456789/4414/1/THESE%20DE%20D [...] Antioxidant, anti-inflammatory and antiulcerogenic activities of Anabasis articulata (Forssk.) Moq.extracts [document électronique] / Yasmina Makhlouf, Auteur ; Amel Bouaziz., Directeur de thèse . - Sétif : Faculté des Sciences de la Nature et de la Vie, 2024 . - 1vol.(166f.) / ill.en coul ; DVD. ISSN : DOC-E/291 Langues : Français Catégories : Thèse et mémoire:Doctorat:Département de biologie et physiologie animale Mots-clés : Anabasis articulata  Analgesic  Gastric ulcer. Résumé : the aim of the present study was to investigate the antioxidant, anti-inflammatory, analgesic and anti-ulcerogenic activities of several extracts of Anabasis articulata, a plant from the Algerian flora of arid and semi-arid regions belonging to the Chenopodiaceae family selected on the basis of an ethnobotanical survey (n=182 respondents) conducted at the El-Mergueb nature reserve.Identification of biomolecules, quantification of secondary metabolites and performance of eight tests to study the antioxidant activity of the extracts: Total antioxidant capacity (TAC),DPPH- 2,2-diphenyl- 1picrylhydrazyl ; ABTS - 2,2′-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid, hydroxyl radical scavenging, metal-chelating hydrogen peroxide scavenging, reducing power test and β-carotene bleaching assay.In vitro anti-inflammatory activity was attested using the ovalbumin denaturation and BSA assay for DEAA,EEAA and their fractions .Molecular docking was performed using Autodock vina. Single oral doses of 2000 and 5000 mg/kg body weight were administered to albino mice to assess acute toxicity. The anti-inflammatory effect was assessed using the carrageenan-induced paw edema model in rats, the croton oil-induced ear edema model and the xylene-induced ear edema model in mice. Analgesic activity was achieved by intraperitoneal injection of acetic acid. Gastroprotective activity was assessed using ethanol-induced gastric ulceration in rats at doses of 50, 100 and 200 mg/kg p.o. for DEAA and 200,400 and 600 mg/kg p.o.for EEAA. The mechanistic study involved pretreatment with appropriate antagonists/ inhibitors such as glibenclamide , indomethacin and L-NAME. 46 plant species belonging to 23 botanical families were identified for the treatment of various ailments.Seven metabolites present in the n-butanol,ethyl acetate and chloroform fractions were qualitatively identified by LC-MS-MS:anthrone,beta-carotene, butylhydroxyanisole, butylhydroxytoluene,gallic acid,myricetin and rutin.The results showed that ChFA represents the largest quantity of total polyphenols and flavonoids. The n-butanol fraction showed the highest amount of total tannins. Quantitative evaluation of DPPH scavenging capacity showed that the ethanolic extract was the most active with IC50 values of 0.074±0.003 mg/mL, the chloroform fraction (ChFA) had the strongest effect in TAC, hydroxyl radical scavenging and hydrogen peroxide scavenging activity with EC50= 0.151±0.0017, IC50= 0.361±0.0087 and IC50= 1.777±0.0402 mg/mL), however,the nbutanol fraction had the highest activity in the ABTS radical scavenging test with an IC50 of 0.021±0.0007 mg/mL. All extracts showed good inhibition of linoleic acid oxidation. Good in vitro anti-inflammatory activity was attested using the ovalbumin denaturation and BSA assays for DEAA,EEAA and their fractions. Molecular docking of the identified biomolecules and the reference drug (indomethacin) revealed good interaction with the inflammatory protein COX2(3LN0).Acute toxicity testing showed that DEAA and EEAA did not cause mortality or adverse effects. Oral administration of 100 or 200 mg/kg of DEAA and EEAA to rats and mice inhibited edema in three tests,with good percentages for both doses of both extracts.The analgesic activity result showed a good effect compared with the standard analgesic (aspirin) for the same doses and extracts. Oral administration of DEAA at doses of 100 mg/kg or 200 mg/kg protected the gastric mucosa against absolute ethanol. Pretreatment with L-NAME,an inhibitor of nitric oxide synthesis, indomethacin,an inhibitor of prostaglandin production,or glibenclamide ,a KATP channel blocker,reversed the gastroprotective activity of (DEAA200 mg/kg, p.o.).DEAA effectively reduced basal gastric juice production without any effect on total acidity. The gastroprotective action of DEAA involved an increase in antioxidant enzymes and mucus secretion. This study provides for the first time the scientific basis for the traditional use of this plant for gastro-preventive effect and supports the traditional use of this plant to treat certain disorders linked to inflammation and oxidative stress.These results can be exploited in the pharmaceutical,food En ligne : http://dspace.univ-setif.dz:8888/jspui/bitstream/123456789/4414/1/THESE%20DE%20D [...]

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Evaluation of antioxidant and anti-inflammatory activities of Stipa tenacissima L decoction. / Bouthaina Djouada / Sétif [Algérie] : Faculté des sciences de la Nature et de la vie, Université Ferhat Abbas Sétif 1 (2025)

Public ISBD Titre : Evaluation of antioxidant and anti-inflammatory activities of Stipa tenacissima L decoction. Type de document : document électronique Auteurs : Bouthaina Djouada, Auteur ; Katia Hamam, Auteur ; Amel Bouaziz., Directeur de thèse Editeur : Sétif [Algérie] : Faculté des sciences de la Nature et de la vie, Université Ferhat Abbas Sétif 1 Année de publication : 2025 Importance : 44 Feuilles ISBN/ISSN/EAN : MS/2235 Langues : Français Catégories : Thèse et mémoire:Master:Physiologie cellulaire et physiopathologie Mots-clés : Stipa tenacissima L  Decoction  Polyphenols  Inflammation  Oxidative stress  antioxidant activity  anti-inflammatory activity. Résumé : Stipa tenacissima L. is a medicinal plant traditionally used in Algeria to treat various health conditions, including weight loss, diabetes, and high blood pressure. In this study, secondary metabolites, antioxidant and anti-inflammatory activities of decoction extract of S. tenacissima were estimated. The aqueous extract was rich in polyphenols and flavonoids with values of 97,02 ± 0,56 mg GAE/g and 50.45 ± 1.65 mg QE/g respectively. Antioxidant activity was evaluated, as demonstrated by the hydrogen peroxide (H₂O₂) scavenging assay (IC50=0.571 ± 0.0252 mg/ml) and the ferric reducing power assay (IC50=0.261 ± 0.006 mg/ml). The anti inflammatory properties were evaluated both in vitro and in vivo. The in vitro egg albumin denaturation test showed an inhibition value of 79.2%, while the xylene-induced ear edema test recorded a reduction in inflammation 72.5% for 100 mg/kg. S. tenacissima was found to be rich in polyphenols and flavonoids and demonstrated effective antioxidant and anti-inflammatory activities across all tests. These findings support the traditional use of S. tenacissima in herbal medicine and suggest its potential as a safe natural remedy for conditions involving inflammation and oxidative stress. Evaluation of antioxidant and anti-inflammatory activities of Stipa tenacissima L decoction. [document électronique] / Bouthaina Djouada, Auteur ; Katia Hamam, Auteur ; Amel Bouaziz., Directeur de thèse . - Sétif (Algérie) : Faculté des sciences de la Nature et de la vie, Université Ferhat Abbas Sétif 1, 2025 . - 44 Feuilles. ISSN : MS/2235 Langues : Français Catégories : Thèse et mémoire:Master:Physiologie cellulaire et physiopathologie Mots-clés : Stipa tenacissima L  Decoction  Polyphenols  Inflammation  Oxidative stress  antioxidant activity  anti-inflammatory activity. Résumé : Stipa tenacissima L. is a medicinal plant traditionally used in Algeria to treat various health conditions, including weight loss, diabetes, and high blood pressure. In this study, secondary metabolites, antioxidant and anti-inflammatory activities of decoction extract of S. tenacissima were estimated. The aqueous extract was rich in polyphenols and flavonoids with values of 97,02 ± 0,56 mg GAE/g and 50.45 ± 1.65 mg QE/g respectively. Antioxidant activity was evaluated, as demonstrated by the hydrogen peroxide (H₂O₂) scavenging assay (IC50=0.571 ± 0.0252 mg/ml) and the ferric reducing power assay (IC50=0.261 ± 0.006 mg/ml). The anti inflammatory properties were evaluated both in vitro and in vivo. The in vitro egg albumin denaturation test showed an inhibition value of 79.2%, while the xylene-induced ear edema test recorded a reduction in inflammation 72.5% for 100 mg/kg. S. tenacissima was found to be rich in polyphenols and flavonoids and demonstrated effective antioxidant and anti-inflammatory activities across all tests. These findings support the traditional use of S. tenacissima in herbal medicine and suggest its potential as a safe natural remedy for conditions involving inflammation and oxidative stress.

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Screening of the antioxidant and hypotensive activities of some medicinal plants in relation to their polyphenolic contents / Amel Bouaziz. / Sétif [Algérie] : Université Sétif 1 Ferhat Abbes (2015) 

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