An Introduction to Computational Systems Biology / Karthik Raman / London : CRC press (2023)   

Public ISBD Titre : An Introduction to Computational Systems Biology : Systems-Level Modelling of Cellular Networks Type de document : texte imprimé Auteurs : Karthik Raman, Auteur Editeur : London : CRC press Année de publication : 2023 Collection : Computational Biology Series Importance : 1 vol. (336 p.) Présentation : ill.en coul. Format : 23 cm ISBN/ISSN/EAN : 978-0-367-75250-7 Langues : Anglais Catégories : Biologie ( B-Cellulaire - B-Animale - B-Végétale - B-moléculaire - Cytologie ) Mots-clés : Systems Biology Index. décimale : 570.285 Informatique appliquée à la biologie et aux sciences de la vie - bio-informatique - Résumé : This book delivers a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks―a fundamental aspect of computational systems biology. The book covers key modelling paradigms in detail, while at the same time retaining a simplicity that will appeal to those from less quantitative fields. Features: * A hands-on approach to modelling * Covers a broad spectrum of modelling, from static networks to dynamic models and constraint-based models * Thoughtful exercises to test and enable understanding of concepts State-of-the-art chapters on exciting new developments, like community modelling and biological circuit design * Emphasis on coding and software tools for systems biology Note de contenu : Sommaire: -1- What is modelling ? -2- Introduction to graph theory -3- Structure of networks -4- Applications of network biology -5- Introduction to dynamic models -6- Parameter estimation -7- Discrete dynamic models: boolean networks -8- Introduction to constraint-based modeling -9- Extending constraint-based approaches -10-Perturbations to metabolic networks An Introduction to Computational Systems Biology : Systems-Level Modelling of Cellular Networks [texte imprimé] / Karthik Raman, Auteur . - London : CRC press, 2023 . - 1 vol. (336 p.) : ill.en coul. ; 23 cm. - (Computational Biology Series) . ISBN : 978-0-367-75250-7 Langues : Anglais Catégories : Biologie ( B-Cellulaire - B-Animale - B-Végétale - B-moléculaire - Cytologie ) Mots-clés : Systems Biology Index. décimale : 570.285 Informatique appliquée à la biologie et aux sciences de la vie - bio-informatique - Résumé : This book delivers a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks―a fundamental aspect of computational systems biology. The book covers key modelling paradigms in detail, while at the same time retaining a simplicity that will appeal to those from less quantitative fields. Features: * A hands-on approach to modelling * Covers a broad spectrum of modelling, from static networks to dynamic models and constraint-based models * Thoughtful exercises to test and enable understanding of concepts State-of-the-art chapters on exciting new developments, like community modelling and biological circuit design * Emphasis on coding and software tools for systems biology Note de contenu : Sommaire: -1- What is modelling ? -2- Introduction to graph theory -3- Structure of networks -4- Applications of network biology -5- Introduction to dynamic models -6- Parameter estimation -7- Discrete dynamic models: boolean networks -8- Introduction to constraint-based modeling -9- Extending constraint-based approaches -10-Perturbations to metabolic networks

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