Résumé :
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Preterm birth (PTB) is a condition that threatens pregnant women between 22 and <37 weeks of pregnancy. It is one of the most important causes of illness and death of neonates, and it is associated with a range of maternal, embryonic and environmental factors. As there are no precise data on the risk factors of this pathological condition in Sétif, this study was carried out in mother and child Hospital in Sétif, to investigate premature birth’s types determined by gestational age with a follow-up and assessment of some biochemical changes in mothers at risk of PTB compared to women who had a term birth. The results showed that most of the women gave birth in the late PTB stage, and health complications were observed in preterm newborns in addition to a rate of deaths. The risk factors for PTB were associated with the age of mother’s marriage, consanguinity, parity, twins, and mother’s health conditions, especially blood pressure, changes in the state of the uterus, the volume of amniotic fluid, and infections. Furthermore, the results of the biochemical parameters showed an increase in the levels of aspartate amino-transferase in women of late PTB and a decrease in the level of uric acid in women of very PTB, with a significant difference of sodium and calcium. This study indicated that there was no significant difference with regard to age, body mass index, sex and fetal weight, potassium, blood components, glycemia, C- reactive protein and renal or hepatic indicators. In conclusion, the importance of early diagnosis with prematurity markers and the identification of women at the highest risk of this condition in our region should be emphasized. This enables early care and effective intervention and enhances awareness during pregnancy to reduce potential complications of PTB.
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