Catalogue de la bibliothèque de SNV
| Titre : | Antioxidant and anti-inflammatory activities of the methanolic extract of Artemisia campestris L. |
| Auteurs : | Kaouther Chellali, Auteur ; Rania Bouzidi, Auteur ; Zineddine Boutefaha, Directeur de thèse |
| Type de document : | document électronique |
| Editeur : | Sétif : Faculté des Sciences de la Nature et de la Vie, 2024 |
| ISBN/ISSN/EAN : | MS/2009 |
| Format : | 36 Feuilles |
| Langues: | Anglais |
| Catégories : | |
| Mots-clés: | Artemisia campestris L. ; Anti-inflmmatory activity ; Antioxidant activity ; Polyphenols ; Flavonoids. |
| Résumé : |
Artemisia campestris, locally known as "T'gouft" and belonging to the Asteraceae family, has been traditionally used in algerian traditional medicine and as a condiment. Artemisia is recognized for its various bioactivities, including anti-inflammatory, antioxidant, and antimicrobial properties. This study aimed to assess the antioxidant and anti-inflammatory potential of Artemisia. The hydro-methanolic extract was analyzed through in vitro tests to evaluate phenolic content and antioxidant activity. Total phenolics and flavonoids were analyzed using Folin-Ciocalteu and aluminum chloride methods and the contents were154.8±2.74μgEqGA/mgand 34.59 ± 0.98μgEqQ/mg of extract, respectively. The antioxidant activity was evaluated using the DPPH assay, revealing a remarkable antioxidant property of the AC extract with an IC50 value of 120.04 ± 1.02μg/ml. Moreover, the methanolic extract showed a highly significant inhibition of paw edema induced by carrageenan in mice, comparable to diclofenac, with 200 and 400 mg/kg doses. These findings support the traditional use of A. campestris in treating inflammatory diseases, highlighting its appreciable anti-inflammatory and antioxidant activities. |
Exemplaires
| Code-barres | Cote | Support | Localisation | Section | Disponibilité |
|---|---|---|---|---|---|
| MS/2009 | BAPP/CD235 | DVD et CD | Bibliothèque SNV | Français | Disponible |
