Catalogue de la bibliothèque de SNV
| Titre : | Evaluation of antioxidant and anti-inflammatory activities of Stipa tenacissima L decoction. |
| Auteurs : | Bouthaina Djouada, Auteur ; Katia Hamam, Auteur ; Amel Bouaziz., Directeur de thèse |
| Type de document : | document électronique |
| Editeur : | Sétif (Algérie) : Faculté des sciences de la Nature et de la vie, Université Ferhat Abbas Sétif 1, 2025 |
| ISBN/ISSN/EAN : | MS/2235 |
| Format : | 44 Feuilles |
| Langues: | Français |
| Catégories : | |
| Mots-clés: | Stipa tenacissima L ; Decoction ; Polyphenols ; Inflammation ; Oxidative stress ; antioxidant activity ; anti-inflammatory activity. |
| Résumé : |
Stipa tenacissima L. is a medicinal plant traditionally used in Algeria to treat various health conditions, including weight loss, diabetes, and high blood pressure. In this study, secondary metabolites, antioxidant and anti-inflammatory activities of decoction extract of S. tenacissima were estimated. The aqueous extract was rich in polyphenols and flavonoids with values of 97,02 ± 0,56 mg GAE/g and 50.45 ± 1.65 mg QE/g respectively. Antioxidant activity was evaluated, as demonstrated by the hydrogen peroxide (H₂O₂) scavenging assay (IC50=0.571 ± 0.0252 mg/ml) and the ferric reducing power assay (IC50=0.261 ± 0.006 mg/ml). The anti inflammatory properties were evaluated both in vitro and in vivo. The in vitro egg albumin denaturation test showed an inhibition value of 79.2%, while the xylene-induced ear edema test recorded a reduction in inflammation 72.5% for 100 mg/kg. S. tenacissima was found to be rich in polyphenols and flavonoids and demonstrated effective antioxidant and anti-inflammatory activities across all tests. These findings support the traditional use of S. tenacissima in herbal medicine and suggest its potential as a safe natural remedy for conditions involving inflammation and oxidative stress. |
Exemplaires
| Code-barres | Cote | Support | Localisation | Section | Disponibilité |
|---|---|---|---|---|---|
| MS/2235 | PCP/CD222 | DVD et CD | Bibliothèque SNV | Englais | Disponible |
