| Titre : | Principles of process research and chemical development in the pharmaceutical industry |
| Auteurs : | O. Repic |
| Type de document : | texte imprimé |
| Editeur : | New York : John Wiley, 1998 |
| ISBN/ISSN/EAN : | 978-0-471-16516-3 |
| Format : | 1 vol. (219 p.) / couv. ill. / 24 cm |
| Langues originales: | |
| Index. décimale : | 615.19 (Chimie pharmaceutique) |
| Catégories : | |
| Mots-clés: | Pharmaceutical chemistry Chemical process control Chemical engineering Technology, Pharmaceutical : methods Chemistry, Pharmaceutical : methods Technologie pharmaceutique : Méthodes Chimie pharmaceutique : Méthodes |
| Résumé : |
This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist of: basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing. |
| Côte titre : |
S8/51390-51391 |
Exemplaires (2)
| Cote | Support | Localisation | Disponibilité |
|---|---|---|---|
| S8/51390 | Livre | Bibliothèque centrale | Disponible |
| S8/51391 | Livre | Bibliothèque centrale | Disponible |
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