| Titre : | Heme Biology : Heme Acts as a Versatile Signaling Molecule Regulating Diverse Biological Processes |
| Auteurs : | Li Zhang, Auteur |
| Type de document : | document électronique |
| Mention d'édition : | 2nd Ed |
| Editeur : | New Jersey : World Scientific, 2020 |
| ISBN/ISSN/EAN : | 978-981-1211300-- |
| Format : | 1 vol. (XVI-266 p.) / ill. en coul. |
| Note générale : | Index |
| Langues: | Anglais |
| Index. décimale : | 572.8 (Génétique moléculaire) |
| Catégories : |
Ouvrages > Sciences naturelles > Sciences de la vie (Biologie) |
| Mots-clés: | Heme Biology |
| Résumé : |
This invaluable book provides the first description of the diverse and fascinating functions of heme in life processes for a broad audience. It begins with an introduction of the intricate chemical properties of heme and the history of early observations of human diseases associated with heme. It then proceeds to describe the versatile roles of heme in controlling diverse molecular and cellular processes germane to human life and disease processes. In the second edition, a new chapter is devoted to describe findings about heme uptake, transport, and trafficking of heme synthesis intermediates in mammals. Additionally, a chapter about the newly discovered roles of elevated heme biosynthesis and uptake in lung tumorigenesis is included. Heme Biology is unified and logical in presentation. It is well suited for students and professionals in life sciences who wish to know about the fascinating biology of heme and its usefulness in health and diseases. It may also be used as a reference book for advanced readers and researchers who are interested in heme biology. The explanations in the book are detailed enough to capture the interest of the curious reader, and complete enough to provide the necessary information for researchers to have an in-depth molecular understanding of heme biology and further their studies in this fascinating realm. |
| Note de contenu : |
Contents: • Introduction: The Fascinating Chemical and Molecular Properties of Heme. • Heme Biosynthesis and Degradation: What Happens When It Goes Haywire?. • Heme Uptake and Transport in Mammals. • Heme: An Ingenious Regulator of Gene Transcription. • Heme-Regulated eIF2α Kinase in Stress Response and Erythropoiesis. • Heme in Brain Functions: Positive and Negative Roles. • Investigating Potential Functions of Heme in MicroRNA Biogenesis. • Heme and Lung Cancer. • The Chemical and Structural Bases of Heme Recognition: Binding Interactions of Heme with Proteins and Peptides. • Clinical Applications of Heme Biosynthetic Pathway: Photodynamic Therapy with Protoporphyrin IX. |
| Côte titre : |
EB/037 |
| En ligne : | https://www.worldscientific.com/doi/epdf/10.1142/11579 |
Exemplaires (1)
| Cote | Support | Localisation | Disponibilité |
|---|---|---|---|
| EB/037 | Livre | Bibliothèque centrale | Disponible |
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