Catalogue de la bibliothèque de SNV
| Titre : | Preparation of Multi-action Topical Cream Using Essential oils of Saccocalyx satureioides Coss. et Durieu and Cymbopogon citratus Stapf. |
| Auteurs : | Souad Chaalal, Auteur ; Daouia Djellali, Auteur ; Abdelhakim Aouf, Directeur de thèse |
| Type de document : | document électronique |
| Editeur : | Sétif : Faculté des Sciences de la Nature et de la Vie, 2024 |
| ISBN/ISSN/EAN : | MS/1943 |
| Format : | 54 Feuilles |
| Langues: | Français |
| Catégories : | |
| Mots-clés: | Essential oils ; Saccocalyx satureioides ; Cymbopogon citratus ; Nanoformulation ; Antibacterial ; Antifungal ; Antioxidant ; Cream. |
| Résumé : |
The need to create novel antimicrobial agents has greatly increased due to escalating concerns about multidrug-resistant bacterial, viral, and fungal strains. Therefore, significant focus has been given to the development of safe, innovative, and alternative antimicrobial substances within the field of antimicrobial therapy. Natural molecules extracted from medicinal plants offer a promising alternative to combating this resistance, with nanoformulation improving their bioavailability and therapeutic effectiveness. This study aimed to evaluate the antimicrobial and antioxidant activities of essential oils (EOs) and their nanoemulsions derived from two aromatic plants, Saccocalyx satureioides and Cymbopogon citratus, using in vitro tests, and to prepare and characterize a topical cream with the extracted essential oils. The antibacterial activity of the EOs was assessed using agar diffusion and disk methods against four pathogenic bacterial strains: Escherichia coli (ATCC 25922) and Klebsiella pneumoniae (ATCC 13883) as Gram-negative bacteria, and Listeria monocytogenes (ATCC 19115) and Methicillin-resistant Staphylococcus aureus (MRSA) (human isolate) as Gram-positive bacteria. The antibacterial efficacy varied depending on the strain and the specific EO used. The EO from S. satureioides (SEO) exhibited a weak antibacterial effect, whereas the EO from C. citratus (CEO) demonstrated notable antibacterial activity. The antifungal activity of these EOs and their nanoemulsions was tested against two pathogenic fungi, Penicillium expansum (isolated strain) and Aspergillus flavus ITEM 698, using the same methods. Both SEO and its nanoemulsion (NSEO) showed significant efficacy, particularly against A. flavus. Additionally, CEO and its nanoemulsion (NCEO) effectively inhibited the growth of both fungal strains. Furthermore, the study evaluated the antioxidant activity of the EOs. The results indicated that SEO, with an IC50 value, was a more effective scavenger compared to NSEO. Conversely, CEO and its nanoemulsion demonstrated a lower scavenging effect. These findings facilitated the synthesis of a topical cream with significant potential for use in both the pharmaceutical and cosmetic industries. The cream contains the studied essential oils, which exhibit exceptionally high antioxidant capacity along with notable antifungal and antibacterial properties |
Exemplaires
| Code-barres | Cote | Support | Localisation | Section | Disponibilité |
|---|---|---|---|---|---|
| MS/1943 | MA/CD320 | DVD et CD | Bibliothèque SNV | Englais | Disponible |
